Lokosa follows a long list of top Nigeria internationals who have featured for the Tunisian club.
Esperance had in the past featured other Nigerian players like Julius Aghahowa, Michael Eneramo, Gabriel Okolosi and Garba Lawal.
Lokosa scored 19 goals before the Nigerian league was halted last year after 24 rounds of matches.
He was capped by the Nigerian national team in a friendly against the Democratic Republic of Congo last year.
